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Measuring residual solvents is mandatory for the release testing of all active chemical ingredients.
Abstract A simple and sensitive method for the simultaneous determination of methanol, ethanol, iso propyl alcohol(IPA), methyl ethyl ketone (MEK), methyl isobutyl ketone (MIBK), n-propyl alcohol (n-PA), ethyl acetate (EA), n-butanol, n-propyl acetate (n-PAc), toluene and ortho-xylene by headspace techniques with FID detection is described. An efficient and sensitive method was successfully developed and validated for the determination of above mentioned solvents of varying polarity used as r...
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